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Dixon plots for the inhibition of DMXAA glucuronidation by amsacrine (a), vinblastine (b) and vincristine (c), and 6-methylhydroxylation by daunorubicin (d) and DACA (e) in human liver microsomes. Concentrations of DMXAA are shown alongside individual plots. Each data point is the mean of at least three determinations.
