Table 1.
Mean arterial pressure, heart rate and blood flow in the infused arm during Study 1.
| ADM (pmol min−1) | PAMP (pmol min−1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Saline | 1 | 3 | 10 | 30 | Saline | 100 | 300 | 1000 | 3000 | |
| FBF (ml 100 ml−1 min−1) | 5.2 ± 0.9 | 5.8 ± 1.0 | 5.8 ± 0.9 | 6.6 ± 1.0 | 8.7 ± 1.2 | 4.2 ± 0.7 | 3.9 ± 0.6 | 5.4 ± 0.8 | 6.8 ± 0.9 | 9.2 ± 1.2 |
| MAP (mmHg) | 86 ± 2 | 89 ± 4 | 87 ± 3 | 87 ± 3 | 92 ± 3 | 92 ± 3 | 93 ± 3 | 91 ± 3 | 90 ± 3 | 90 ± 3 |
| Heart rate (beats min−1) | 65 ± 1 | 69 ± 3 | 68 ± 2 | 64 ± 3 | 66 ± 3 | 66 ± 1 | 65 ± 3 | 65 ± 4 | 65 ± 3 | 65 ± 2 |
ADM = adrenomedullin; PAMP = proadrenomedullin NH2-terminal 20 peptide; FBF = absolute blood flow in the infused forearm; MAP = mean arterial pressure. Values are means ± s.e. mean, n = 8.