Table 2.
Mean arterial pressure, heart rate and blood flow in the infused arm during Study 2.
| Thiorphan | Noradrenaline | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Adrenomedullin (pmol min−1) | Baseline | 1 | 3 | 10 | 30 | Baseline | 1 | 3 | 10 | 30 |
| FBF (ml 100 ml−1 min−1) | 3.9 ± 0.7 | 4.1 ± 0.7 | 4.5 ± 0.6 | 5.5 ± 0.7 | 7.2 ± 0.8 | 4.1 ± 0.8 | 3.9 ± 0.6 | 4.0 ± 0.7 | 4.2 ± 0.8 | 4.7 ± 0.8 |
| MAP (mmHg) | 91 ± 3 | 88 ± 2 | 88 ± 1 | 87 ± 2 | 90 ± 2 | 91 ± 4 | 93 ± 4 | 92 ± 3 | 92 ± 3 | 94 ± 3 |
| Heart rate (beats min−1) | 59 ± 1 | 54 ± 2 | 59 ± 1 | 60 ± 1 | 58 ± 2 | 63 ± 2 | 63 ± 2 | 64 ± 2 | 63 ± 2 | 63 ± 1 |
FBF = absolute blood flow in the infused forearm; MAP = mean arterial pressure. Values are means ± s.e. mean, n = 8.