Table 1.
ADRs detected from ICD codes and Yellow Card reports during the period of study
| ICD coded ADRs | Yellow cards |
|---|---|
| Anticoagulants | Cardiovascular drugs |
| warfarin haemorrhage (9 cases) | digoxin and trimethoprim digoxin toxicity (serious) |
| Cardiovascular drugs | Central nervous system drugs |
| β-adrenoreceptor antagonists bradycardia (3 cases) | paroxetine haemolytic anaemia (fatal) |
| frusemide dehydration (2 cases) | thioridazine ventricular fibrillation associated with long QT interval (serious) |
| indapamide hyponatraemia | sulpiride abnormal liver function (serious) |
| bendrofluazide hyponatraemia | amisulpiride fitting (serious) |
| digoxin confusion | paroxetine bruxism |
| Central nervous system drugs | Anti-fungals |
| paroxetine hyponatraemia | clotrimazole cream blistering of skin |
| chlorpromazine extrapyramidal reaction | terbinafine pityriasis rosea |
| clonazepam extrapyramidal symptoms | NSAIDS |
| clozapine neutropenia | diclofenac gastro-intestinal bleeding (serious) |
| lamotrigine carbamazepine toxicity | aspirin gastro-intestinal bleeding (serious) |
| diazepam acute confusional state | Other drugs |
| NSAIDS | Premarin® (conjugated oestrogens) pulmonary embolus (serious) |
| aspirin eye socket, lip swelling, and urticarial rash | prochlorperazine extrapyramidal reaction (serious) |
| aspirin and diclofenac gastric erosion | latanoprost cystoid macular oedema (serious) |
| aspirin duodenitis | iopamidol cerebral artery vasospasm (serious) |
| Antibacterials | |
| penicillin anaphylaxis (3 cases) | |
| penicillin rash | |
| amoxicillin bloody diarrhoea | |
| Vaccines | |
| diptheria tetanus pertussis vaccine eyes rolling and shaking | |
| Endocrine drugs | |
| insulin hypoglycaemia |