Table 2.
Anti-Xa activity in plasma and breast milk.
| Patient number | IU ml−1 plasma* | IU ml−1 breast milk* | Milk/plasma ratio |
|---|---|---|---|
| 01 | 0.191 | 0.017 | 0.089 |
| 02‡ | 0.308 | 0.006 | 0.02 |
| 03 | 0.201 | 0.012 | 0.06 |
| 04 | 0.087 | 0.017 | 0.195 |
| 05 | 0.260 | 0.027 | 0.104 |
| 06 | 0.264 | 0.012 | 0.046 |
| 07 | 0.192 | <0.005+ | <0.026 |
| 08 | 0.198 | <0.005+ | <0.025 |
| 09 | 0.103 | 0.017 | 0.165 |
| 10 | 0.180 | <0.005+ | <0.028 |
| 11 | 0.165 | 0.037 | 0.224 |
| 12 | 0.254 | 0.021 | 0.083 |
| 13 | 0.175 | 0.028 | 0.16 |
| 14 | 0.074 | <0.005+ | <0.068 |
| 15 | 0.163 | 0.007 | 0.043 |
Anti-Xa activity determined using a clotting time assay developed and performed by P. Lang, Quality Control & Assurance, F. Hoffmann-La Roche, Basel, Switzerland.
+Limit of quantification was set at the lowest point on the standard calibration curve plotted for each sample (t = 0).
The recovery rate for a 0.045 IU ml−1 spike of low molecular weight heparin added to the plasma of this patient (t = 0) was 88.9%.