Table 3.

Regression models which describe relationships between AmB pharmacokinetic parameters and influential patient covariates.

Regression model	Regression coefficients (θ) mean (s.d.)	F-test	Significance
CL (l h−1) = θ1 + θ2 WT0.75 + θ3 DF	θ1: 0.053	44.5	P < 0.005
	θ2: 0.046 (0.006)
	θ3: 0.242 (0.040)
V (l) = θ4 + θ5 WT	θ4: 7.106	6.3	P < 0.025
	θ5: 0.107 (0.043)

WT=weight (kg), WT^0.75=weight^0.75 (kg), DF=method of AmB administration: dextrose infusion was coded 1 and lipid emulsion infusion was coded 2.

θ=regression coefficient, s.d.=standard deviation.