Table 1.

Distribution of l-asparagine concentrations in plasma for enzyme activities below 100 IU l⁻¹.

l-asparagine concentration	% samples (n)	Number of patients
Complete depletion ≤0.2 µm*	67.6 (23)	17
Almost complete depletion >0.2–≤0.5 µm	8.8 (3)	3
Moderate reduction >0.5–≤1 µm	–	–
Slight reduction >1–≤25 µm	5.9 (2)	1
No reduction >25 µm	17.6 (6)	4
Total	100 (34)#	19

^*limit of detection.

^#In 35 plasma samples the enzyme activity was <100 IU l⁻¹. In one case there was not enough material for determination of the concentration of l-asparagine.