Table 2.
Assay interoccasion precision and accuracy for artemisinin and dihydroartemisinin based on the analyses of quality control (QC) samples interspersed with authentic samples on each experimental occasion.
Precisiona (%) | Accuracyb (%) | |
---|---|---|
Artemisinin QCs (n > 38) | ||
293.6 nmol l−1 | 7.8 | 103 |
(100, 106) | ||
2936 nmol l−1 | 5.2 | 99 |
(97, 100) | ||
5872 nmol l−1 | 8.0 | 100 |
(98, 103) | ||
Dihydroartemisinin QCs | ||
911 nmol l−1 (n = 7) | 11.9 | 111 |
(99–123) | ||
4234 nmol l−1 (n = 11) | 7.5 | 105 |
(100–110) |
Intermediate precision expressed as the relative standard deviation (% coefficient of variation) of found concentrations.
Closeness of agreement between found and theoretical concentrations calculated as 100 ○ measured concentration/theoretical concentration as mean (95%).