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. 2001 Nov;52(5):521–527. doi: 10.1046/j.0306-5251.2001.01486.x

Table 1.

Mean AUCi.n./AUCi.v.ratios (expressed as percentage) at various times after the administration of 4 and 7 mg diazepam to seven healthy subjects.

AUCi.n./AUCi.v. (%) Time (min)
I.n.dose 3 5 8 11 15 20 30 45 60
4 mg 12a 14 17 21 25 29 34 40 45
7 mg 7a 8 12 15 19 22 27 34 42
P valueb 0.07 0.05 0.09 0.14 0.17 0.12 0.09 0.19 0.63
a

One AUC value was left out because it was thought to be an outlier, being more than three times the standard deviation above all the other values.

b

P values from the comparison between the two doses.