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Effect of medetomidine (MED) on DMPP-evoked overflow of noradrenaline and adrenaline from the adrenal medulla of wild-type mice. Concentration–inhibition curves were obtained by adding MED (0.1–300 nM) 15 min before DMPP (500 μM). Results are presented as percentage inhibition. Symbols and vertical lines represent mean±s.e.m. (n=5).
