Table 1.

Spontaneous outflow (in % of NA or AD adrenal content per minute) and DMPP-evoked overflow (in fraction of increase of spontaneous outflow) of NA and AD from the adrenal medulla WT and KO mice for each of the three α₂ adrenoceptor subtypes (α_2A, α_2B and α_2C)

	WT	α2AKO	α2BKO	α2CKO
Spontaneous outflow
NA	0.37±0.02	0.70±0.04*	0.79±0.06*	0.75±0.02*
AD	0.59±0.05	0.99±0.06*	0.95±0.02*	0.97±0.05*
DMPP-evoked overflow
NA	4.59±0.39	5.03±0.57	4.10±0.50	4.86±0.29
AD	2.56±0.27	2.28±0.18	2.36±0.19	2.28±0.10

Abbreviations: AD, adrenaline; DMPP, 1,1-dimethyl-4-phenylpiperazinium; KO, knockout; NA, noradrenaline; WT, wild type.

Values are presented as mean±s.e.m. (n=6).

^*Significantly different from corresponding values in WT mice P<0.05.