Table 1.
Model parameter estimates for brain kinetics of M6G in 5 sheep
| Model | V1 (ml) | PS (ml/min) | V2 (ml) | Residual error (% CV) |
|---|---|---|---|---|
| Flow-limited | ||||
| Parameter value | 14.5 (26%) | — | — | 35 (14%) |
| Inter-animal variability (%CV) | 29 (93%) | — | — | |
| Flow-limited with lossa | ||||
| Parameter value | 14.5 | 2.2 × 10−9 | — | 35 |
| Inter-animal variability (%CV) | 29 | — | — | |
| Membrane-limited | ||||
| Parameter value | 13.7 (27%) | 2.5 (85%) | 18.4 (50%) | 35 (14%) |
| Inter-animal variability (%CV) | 29 (90%) | — | — |
Data are the value of the population estimate, with data in parentheses indicating the % s.e. of the parameter estimate indicating the reliability of the parameter estimate.
a
Covariance step failed and % SE of parameter estimates are not available.