Table 1.

Effect of J-113863 on the DTH response induced by DNFB in the ears of mice and on the plasma levels of IL-2 induced by SEB

Treatment	Dose (mg kg−1)	DTH Biopsy weight (mg) mean±s.e.m.	SEB IL-2 (pg ml−1) mean±s.e.m.
Vehicle	—	15.1±1.3	3563±53
J-113863	3	14.9±1.0	3650±89
	10	15.5±2.0	3554±196
	30	14.9±1.3	3380±180
Dexamethasone	3	6.9±0.7*	1400±120*

Dexamethasone was used as a reference standard. Results shown are representative of two independent experiments using six mice per group.

^*P<0.05 vs vehicle-treated mice, Student's t-test.