Table 3.

Effect of J-113863 on the spontaneous release of TNFα and IL-10 by cultured synovial membrane cells from arthritic patients

Treatment	(M)	TNFα(ng ml−1) mean±s.d.	IL-10 (ng ml−1) mean±s.d.
Vehicle	—	1.32±0.74	1.58±0.17
J-113863	10−9	1.55±0.89	2.21±0.62*
	10−8	1.66±0.83	2.21±0.82*
	10−7	1.94±0.72	1.90±0.46

Results shown are the mean and s.d. of samples from two independent experiments performed in triplicate.

^*P<0.05 vs vehicle (Student's t-test).