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Effects of 5-hydroxyindole (5-OHi) on the nAChR agonist-mediated overflow of [3H]D-aspartate ([3H]D-ASP) from mouse cortical synaptosomes. 5-OHi was added 8 min before agonists. Data are mean ±s.e.mean of 4–9 experiments run in triplicate (three superfusion chambers for each experimental condition). *P<0.05; **P<0.01 versus control (two-tailed student's t-test).
