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(a) Western blot analysis of hERG WT channel protein with increasing concentrations of fluoxetine, norfluoxetine, E4031 and cisapride. (b) IhERG traces (square pulse protocol, see Figure 3a) for control conditions (left panel), following 24 h incubation without drug washout or after 1 h drug-free conditions for 10 or 30 μM fluoxetine (middle panels), and IhERG 1 h following washout of 5 μM E4031 (right panel).
