Table 1.
A list of genes whose transcripts are associated with PRPF31-containing complex as detected by immunoprecipitation-coupled microarray experiment.
| Gene Function | Genbank number | Gene Name |
|---|---|---|
| A. Photoreceptor structure & phototransduction or visual cycle | ||
| BC013125.1 | rhodopsin | |
| NM_007538.1 | blue opsin | |
| NM_008938.1 | peripherin 2 | |
| NM_009073.1 | rod outer segment membrane protein 1 (Rom1) | |
| NM_172802 | fascin homolog 2 | |
| NM_012065.1 | phosphodiesterase 6G, cGMP-specific, rod, gamma (Pde6g) | |
| NM_008806.1 | phosphodiesterase 6B (PDE6B) | |
| NM_008801.1 | phosphodiesterase 6D, cGMP-specific, rod, delta (Pde6d) | |
| NM_020599.1 | retinaldehyde-binding protein 1 (Rlbp1) | |
| BC017610.1 | Similar to retinol-binding protein 3, interstitial | |
| NM_007378.1 | ATP-binding cassette, sub-family A, member 4 (Abca4) | |
| NM_024458.1 | rod photoreceptor 1 (Rpr1) | |
| AF155141.2 | oxygen-regulated photoreceptor protein 1 (Rp1) | |
| NM_009038.1 | recoverin (Rcvrn) | |
| B. Cell proliferation & cell death genes | ||
| NM_008015.1 | fibroblast growth factor inducible 14 | |
| NM_007610.1 | caspase 2 | |
| NM_007611.1 | caspase 7 | |
| NM_011997.1 | caspase 8 associated protein 2 | |
| NM_011810.1 | Fas apoptotic inhibitory molecule (Faim) | |
| NM_009628.1 | activity-dependent neuroprotective protein | |
| NM_011051.1 | programmed cell death 6 (Pdcd6) | |
| AF100927.1 gb:BC003292.1 g| | programmed cell death 8 (Pdcd8, apoptosis inducing factor) | |
| NM_007465.1 | apoptosis inhibitor 2 | |
| NM_007466.1 | apoptosis inhibitor 5 | |
| AF011908.1,NM_007377.1 | apoptosis-associated tyrosine kinase (Aatk) | |
| C. Synaptic transmission& neuronal functions | ||
| NM_009306.1 | synaptotagmin 1 (Syt1), mRNA | |
| NM_011428.1 | synaptosomal-associated protein, 25kD | |
| NM_013669.1 | synaptosomal-associated protein 91 kDa (Snap91) | |
| M92378.1 | gamma-aminobutyric acid (GABA-A) transporter 1 (Gabt1) | |
| NM_020590.2 | GABA-A receptor-associated protein-like protein1 | |
| AV075715 | clusterin | |
| D. Transcription or RNA processing or translation | ||
| NM_007770.1 | cone-rod homeobox containing gene (Crx) | |
| NM_008736.1 | neural retina leucine zipper gene (NRL) | |
| AF201285.1 | TSC22-related inducible leucine zipper 1b | |
| NM_013708 | nuclear receptor subfamily 2, group E, member 3 (Nr2e3) | |
| AF443223.1 | PAX6 | |
| BB722680 | heterogeneous nuclear ribonucleoprotein K | |
| NM_011732.1 | Y box protein 1 | |
| NM_007705.1 | cold inducible RNA binding protein (Cirbp) | |
| BC009142.1 | DEAD (aspartate-glutamate-alanine-aspartate) box polypeptide 5 (Ddx5) | |
| NM_009159.1 | splicing factor, arginineserine-rich 5 (SRp40, HRS) | |
| NM_013670.1 | small nuclear ribonucleoprotein N (Snrpn) | |
| NM_020007.1 | muscleblind-like (Mbnl) | |
| NM_010655.1 | karyopherin (importin) alpha 2 | |
| BC018223.1 | eukaryotic translation elongation factor 1 alpha1 | |
| E. Cell metabolism & stress responses | ||
| NM_011829.1 | inosine 5-phosphate dehydrogenase 1 (IMPDH1) | |
| AV218207 | cytochrome c oxidase, subunit Vb | |
| NM_053071.1 | cytochrome c oxidase 6c (Cox6c) | |
| NM_016774.1 | ATP synthase, H+ transporting mitochondrial F1complex, alpha subunit | |
| AF354051.1 gb:BC016547.1 | ATP-synthase subunit D | |
| AV212820 | ATPase, H+ transporting, lysosomal 16kD, V0 subunit C | |
| NM_033617.1 | ATPase, H+ transporting, lysosomal 21kDa | |
| BC027319.1 | ATPase, Na+K+ transporting, beta 1 polypeptide | |
| BC011114.1 | NADH dehydrogenase (ubiquinone) 1 alphasubcomplex, 4 | |
| BG967663 | creatine kinase | |
| NM_011099.1 | pyruvate kinase 3 (Pk3) | |
| NM_022310.1 | heat shock 70kD protein 5 (glucose-regulated protein, 78kD) (Hspa5) | |
| BG242724 | heat shock protein, 86 kDa 1 (Hsp86-1) | |
| F. Signal transduction & protein modification | ||
| NM_013636.1 | protein phosphatase 1, catalytic subunit, gamma isoform (Ppp1cc) | |
| NM_008140.1 | guanine nucleotide binding protein, alphatransducing 1 | |
| NM_008142.1 | guanine nucleotide-binding protein, beta-1subunit (Gnb1) | |
| U60001.1 | protein kinase C inhibitor | |
| BC003461.1,BC005697.1 | protein kinase, cAMP dependent regulatory, type I, alpha (Prkar1a) | |
| NM_009790.1 | calmodulin 1 | |
| NM_007597.1 | calnexin | |
| NM_013746.1 | PH domain containing protein in retina 1 (Phret1) | |
| NM_008907.1 | peptidylprolyl isomerase A (Ppia) | |
| BB206460 | phosphatidylinositol membrane-associated (Pitpnm) | |
| G. Other & Unknown function | ||
| M20480.1 | neurofilament-L | |
| NM_008633.1 | microtubule-associated protein 4 (Mtap4) | |
| AF483486.1 | cystatin C | |
| BC021403.1, BF135781 | ADP-ribosylation factor 1 | |
| BG065457 | aldolase 1, A isoform | |
| AF085681.1 | tubby like protein 1 (Tulp1) | |
| AF277093.1 | Elovl4 | |
| NM_130878.1 | photoreceptor cadherin | |
| AV261043 | EST similar to SUPEROXIDE DISMUTASE | |
| BC026372.1 | Nedd4 WW binding protein 5 | |
| BC004625.1 | neural precursor cell expressed, developmentallydown-regulated gene 8 (Nedd8) | |