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Effect of V3 and C4 mutations on CCR5-dependent cell-cell fusion as measured by a reporter gene activation assay. β-Gal activity is expressed as a percentage of that seen with the wild-type (WT) clone, HXB2-JRFL. White bars indicate values (mean plus one standard deviation) less than 50%. Gray bars indicate mean values that are 50%. Data shown represent the means and standard deviations of data from at least three independent experiments.
