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. Author manuscript; available in PMC: 2007 Oct 10.

Published in final edited form as: Virology. 2006 Nov 13;360(1):182–190. doi: 10.1016/j.virol.2006.10.019

Fig. 3 — (A) Effect on gp120-sCD4 binding, as measured by ELISA, for V3 and C4 mutations that were found to reduce cell-cell fusion by approximately 2-fold or more. The gray bar indicates a mean value less than 50% of WT. Data shown represent the means and SD of data from three independent experiments. (B) A representative western blot of envelope proteins in viral lysates for V3 and C4 mutants that decreased CCR5-dependent cell fusion by approximately 2-fold or more. Pooled sera from individuals infected with HIV-1 subtype B was used to detect the expression of envelope proteins. The positions of the gp120 and p24 bands are labeled.

Fig. 3 — (A) Effect on gp120-sCD4 binding, as measured by ELISA, for V3 and C4 mutations that were found to reduce cell-cell fusion by approximately 2-fold or more. The gray bar indicates a mean value less than 50% of WT. Data shown represent the means and SD of data from three independent experiments. (B) A representative western blot of envelope proteins in viral lysates for V3 and C4 mutants that decreased CCR5-dependent cell fusion by approximately 2-fold or more. Pooled sera from individuals infected with HIV-1 subtype B was used to detect the expression of envelope proteins. The positions of the gp120 and p24 bands are labeled.