Table III.

Summary of clinical and molecular data for seven Chinese families carrying the G11778A mutation

Pedigree	Ratio (affected male/female)	Average age of onset (yr)	Numbers of matrilineal relatives	Penetrance (%)a	Secondary mtDNA mutation	mtDNA haplogroup
WZ12	3.5:1	18	30	33	G11696A	D4
WZ1b	6:0	22	38	16		B5
WZ2 c	3:1	14	14	57	A4435G	D5
WZ3 d	2:1	19	10	60	A15591G	D4
WZ4 e	3:0	17	9	33		F1
WZ5	1:1	20	14	36		D4b2b
WZ6	1.2:1	18	31	36		M10a

^aAffected matrilineal relatives/total matrilineal relatives;

^bQu et al. (2005)

^cQu et al (2006)

^dLi et al (2006)

^eQian et al (2005)