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E-D model of prostate cancer
| Hormone receptor | Property |
| Membrane androgen receptor | ↑apoptotic proteins ↑bcl-2 ↑calreticulin |
| Intracellular androgen receptor | ↓apoptotic proteins ↓bcl-2 |
| Estrogen receptor-αβ heterodimer | ↑telomerase activity |
| Estrogen receptor-α | ↑bcl-2 |
| Estrogen receptor-β | ↓bcl-2 |
