Table 1.
Inherited and epigenetic mtDNA variability. The number of subjects classified within a specific haplogroup is reported together with the number of subjects showing heteroplasmy levels higher than 5%. MtDNA haplogroups are classified according to Torroni et al., [27].
| MtDNA Haplogroup | Centenarians | Controls | ||
| Absolute frequency | Heteroplasmic subjects | Absolute frequency | Heteroplasmic subjects | |
| H | 35 | 15 | 34 | 10 |
| I | 2 | 2 | 0 | 0 |
| J | 11 | 8 | 17 | 7 |
| K | 10 | 6 | 16 | 6 |
| T | 6 | 3 | 10 | 3 |
| U | 13 | 7 | 11 | 4 |
| V | 1 | 1 | 1 | 0 |
| W | 2 | 1 | 4 | 3 |
| X | 9 | 8 | 5 | 3 |
| Other | 11 | 4 | 16 | 6 |
| Total | 100 | 55 | 114 | 47 |