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Heteroplasmic sites identified by sequencing mtDNA CR (16531 nt_261 nt) in subjects showing DHPLC heteroplasmy levels equal to or higher than 25%.
| Mutations | |||||
| G62A | T146C | C150T | T152C | G189A | |
| Centenarians | 1 | 1 | 4 | 1 | |
| Offspring of centenarians | 1 | 4# | 1 | ||
| Controls | 2* | 1 | |||
# One of the 4 children showing C150T heteroplasmy was the son of one of the 4 centenarians displaying C150T heteroplasmy.
* Subjects showing heteroplasmy for both T146C and C150T mutations.
