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. Author manuscript; available in PMC: 2007 Oct 10.
Published in final edited form as: J Allergy Clin Immunol. 2005 Nov 8;116(6):1235–1241. doi: 10.1016/j.jaci.2005.09.016

TABLE III.

Univariate biometric genetic models for asthma and obesity

  Estimates of variance components
Tests of model fit
Model* Additive genetic (A) Common environment (C) Unique environment (E) χ² df P Value AIC
Asthma              
  ACE 0.35 (0.00–0.62) 0.17 (0.00–0.52) 0.49 (0.38–0.60) - - - -
  AE 0.53 (0.41–0.63) - 0.47 (0.37–0.59) 0.62 1 .43 1.38
  CE - 0.46 (0.36–0.56) 0.54 (0.44–0.64) 2.37 1 .12 0.37
Obesity              
  ACE 0.77 (0.40–0.83) 0.00 (0.00–0.34) 0.23 (0.17–0.32) - - - -
  AE 0.77 (0.68–0.83) - 0.23 (0.17–0.32) 0.00 1 1.00 2.00
  CE - 0.66 (0.58–0.73) 0.34 (0.27–0.42) 17.89 1 <.0001 15.89
*

ACE refers to a model that includes additive genetics (A), common environment (C), and unique environment (E); AE only includes additive genetics and unique environment; and CE only includes the common and unique environment.

Proportion of variance caused by additive genetics (a²), shared environment (c²), and unique environment (e²) according to each model.

Akaike’s information criterion (AIC) is a global measure of goodness of fit; the best-fitting and most parsimonious models are shown in bold.