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Enantioselective glucuronidation of formoterol by human liver microsomes. (a) Velocity vs substrate concentration and (b) corresponding Eadie-Hofstee plots for incubation of (a1) and (b1) single enantiomers and (a2) and (b2) rac-formoterol with human liver microsomes. Microsomal protein concentration 600 μg ml−1, incubation time 60 min.
(S; S)-formoterol; o (R; R)-formoterol. Data points represent the median values for nine human livers.
