Figure 3.

The effects of milnacipran (▪), amitriptyline (▴) and placebo (♦) on subjective ease of awakening from sleep, as measured by the AFS component of the LSEQ. A higher score represents more subjectively perceived difficulty in waking up. Values are plotted as differences from baseline, over the three dose days. There were no significant differences between milnacipran and placebo at any time point. Amitriptyline, however, produced greater subjective difficulty in waking compared to placebo.