Table 3.

Geometric mean ratios and 95% confidence intervals for the comparison of the pharmacodynamic parameters AUE(0,12 h) and AUE(0,24 h) derived from the inhibition of ADP- and collagen-induced platelet aggregation vs time curves for treatment C (sibrafiban+ticlopidine+aspirin) versus treatment A (sibrafiban) and treatment C (sibrafiban+ticlopidine+aspirin) versus treatment B (ticlopidine+aspirin).

	Geometric mean ratio C/A	Geometric mean ratio C/B
ADP-induced platelet aggregation
AUE(0,12 h) ratio	1.90 [1.29–2.79]	1.26 [0.86–1.85]
AUE(0,24 h) ratio	1.88 [1.15–3.06]	1.01 [0.62–1.65]
Collagen-induced platelet aggregation
AUE(0,12 h) ratio	4.07 [2.14–7.76]	1.03 [0.54–1.96]
AUE(0,24 h) ratio	3.51 [1.91–6.46]	0.84 [0.46–1.54]