Table 7.
Examples of complications which resolved on re-institution of preadmission medicines.
| Diagnosis/age | Drug withdrawn | Symptoms | Consequences | Resolution |
|---|---|---|---|---|
| Breast cancer with secondary deposits | ||||
| 63 years | Nitrazepam | Psychotic, confused, drowsy | ? cerebral mets, CT scan, lumbar puncture, power of attornery withdrawn permanently, lawyers involved, family rifts | Diazepam started once nitrazepam withdrawal recognized as cause of symptoms, lucid within 12 h. |
| Abdominal aortic aneurysm repair | ||||
| 75 years | Sinemet | Movements difficult during this time | Mobilization delayed and chest complications | Symptoms resolved once Sinemet re-introduced day 9 postop. |
| Aorto-bi-iliac graft | ||||
| 85 years | Doxepin | Tearful, anxious and depressed | Mobilization delayed | Doxepin reintroduced 23 days later and patient much improved |
| Caecopexy | ||||
| 66 years | Sinemet | Movements difficult during this time | Mobilization delayed and chest complications | Symptoms resolved once Sinemet re-introduced. |
| Aorto-bi-iliac graft | ||||
| 63 years | Sotalol, lisinopril | Day 1 postop pulmonary oedema and systolic BP > 200 mmHg despite adequate pain control and other causes eliminated, day 6 started sips, and hypertensive again | Needed prn nifedipine sl to control hypertension | Admission meds re-instated day 6 and became normotensive. |
| Left hemicolectomy/anterior resection | ||||
| 67 years | Captopril, pindolol, bumetanide | Day 2 systolic BP > 200 mmHg despite adequate pain control and other causes eliminated. Also BP became quite labile. Day 7 bp 175/90 mmHg | Intravenous metoprolol given until day 5 and nifedipine sl until day 8 | Captopril restarted day 8, became normotensive |
| Abdominoperineal resection | ||||
| 69 years | Viskaldix | Steady rise in BP. Day 4190/100 mmHg + headache | Still ‘nbm’ but Visaldix recommenced | Normotensive day 4 and fluids introduced day 6. |
| Transverse colectomy | ||||
| 64 years | Cyclopenthiazide, diltiazem | |||
| Day 3 BP 200/130 mmHg | Pain from concurrent osteoarthritis Mobilization a problem because of NSAID withheld | Needed 3 dose of nipedipine to become normotensive Restarted on diltiazem and became normotensive | ||
| Abdominoperineal resection | ||||
| 67 years | Enalapril, nadolol | Hypertensive, 190/120 mmHg (Day 1) 200/116 mmHg (Day 2) 230/120 mmHg (Day 3) | Needed prn nifedipine sl to control hypertension | Admission meds re-instated day 3 and became normotensive. |
| Anterior resection | ||||
| 65 years | Enalapril | Day 3 hypertensive 190/110 mmHg | Re-started admission meds | Admission meds re-instated day 3 and became normotensive |