Table 2.

Incidence rates of and relative risks of acute pancreatitis for individual acid-suppressing drugs.

	Person-years	Cases	IR/105	Crude RR (95% CI)	RR (95% CI)*
Non-users†	160430	7	4.4
Current-use‡	141738	14	9.9	2.3 (0.9,5.6)	1.6 (0.6,4.2)
cimetidine	35966	5	13.9	3.2 (1.0,10.0)	2.3 (0.7,7.7)
famotidine	1551	0	–
lansoprazole	4567	0	–
nizatidine	4262	0	–
omeprazole	38430	3	7.8	1.8 (0.5,6.9)	1.3 (0.3,5.3)
ranitidine	56961	6	10.5	2.4 (0.8,7.2)	1.7 (0.6,5.4)
Past use§	196356	15	7.6	1.8 (0.7,4.3)	1.6 (0.6,4.0)

^*Age, gender and calendar year were included in the Poisson regression model.

^†No use of an acid-suppressing drug in the 371 days precedingthe index date.

^‡Use of an acid-suppressing drug on the index date or the 6 days preceding the index date.

^§Use of an acid-suppressing drug indays 7–371 before the index date.