Table 3.

Relative risk of acute pancreatitis associated with use of acid-suppressing drugs and other factors.

	Cases (n = 36)	Controls (n = 1000)	OR (95% CI)
Acid-suppressing drug
Non-use†	7	306
Current use‡	14	263	1.4 (0.5,3.6)
cimetidine	5	65	2.1 (0.6,7.2)*
omeprazole	3	69	1.1 (0.3,4.6)*
ranitidine	6	129	1.3 (0.4,4.1)*
Past users§	15	431	1.3 (0.5,3.3)*
Age
20–59 years	12	639
60–74 years	24	361	3.1 (1.5,6.4)
Gender
Male	20	486
Female	16	514	0.6 (0.3,1.2)
Year category‖
1992–94	16	400
1995–97	20	600	0.9 (0.5,1.8)
Pancreatoxic medication
Non-use	21	760
Current use	15	240	2.0 (1.0,4.2)

^*Adjusted for age, gender, calendar year, and current use of other pancreatoxic medication.

^†No use of an acid-suppressing drug in the 371 days preceding the index date.

^‡Use of an acid-suppressing drug on the index date or within the 6 days preceding the index date.

^§Use of an acid-suppressing drug in days 7–371 before the index date.

^‖End of study in September 1997.