Table 4.
Influence of duration of acid-suppressing drug therapy on the risk of acute pancreatitis.
Cases (36) | Controls (1000) | OR (95% CI)* | |
---|---|---|---|
Duration of antiulcer therapy† | |||
≤ 30 days | 3 | 47 | 2.3 (0.5–9.5) |
> 30 days | 11 | 234 | 1.1 (0.4–3.3) |
Daily dose of cimetidine†, ‡ | |||
< 800 mg | 2 | 22 | 2.2 (0.4–12.6) |
≥ 800 mg | 3 | 41 | 1.7 (0.4–7.7) |
Daily dose of ranitidine†, § | |||
< 300 mg | 2 | 26 | 1.9 (0.3–10.3) |
≥ 300 mg | 4 | 100 | 1.1 (0.3–4.2) |
Adjusted for age, gender, calendar year, and current use of other pancreatoxic medication.
Current use compared with nonuse.
Data on daily dose of cimetidine was not available for two controls.
Data on daily dose of ranitidine was not available for three controls.