Table 1.
Risk of intracranial haemorrhage associated with the use of antidepressants for all cases combined.
| Cases (n =65) | Controls (n =247) | Adjusted* Odds ratio (95% CI) | ||
|---|---|---|---|---|
| Non use | 44 | 160 | 1 (reference) | |
| Current use** | ||||
| SSRI | 7 | 24 | 0.9 (0.4,2.4) | |
| Other antidepressants | 11 | 51 | 0.8 (0.4,1.6) | |
| Recent use | 3 | 12 | 0.8 (0.2,3.1) | |
Adjusted for age, sex, calendar time and practice (the adjustment for hypertension, smoking, body mass index, asthma/COPD, migraine and NSAID use did not change the estimates)
Two subjects (one case and one control) used two different antidepressants within the 30 days period prior to the index date, and were classified according to the last antidepressant prescribed