Table 3.
Risk of intracerebral haemorrhage associated with the use of antidepressants.
| Cases (n = 29) | Controls (n = 114) | Adjusted* odds ratio (95% CI) | |
|---|---|---|---|
| Antidepressant use | |||
| Non use | 19 | 76 | 1 (reference) |
| Current use | |||
| SSRI | 3 | 9 | 0.8 (0.1,5.6) |
| Other antidepressants | 5 | 21 | 1.0 (0.2,4.9) |
| Recent use | 2 | 5 | 0.5 (0.0,15.8) |
| Hypertension | 10 | 19 | 3.8 (1.0,14.5) |
| Smoking | |||
| Never | 9 | 64 | 1 (reference) |
| Current | 13 | 22 | 5.9 (1.2,28.1) |
| Ex-smoker | 1 | 7 | 3.0 (0.2,54.3) |
| Unknown | 6 | 18 | 1.3 (0.2,7.2) |
| Body mass index | |||
| <25 | 7 | 48 | 1 (reference) |
| 25-29 | 2 | 38 | 0.6 (0.1,3.7) |
| 30+ | 7 | 9 | 7.6 (1.1,55.3) |
| Unknown | 13 | 16 | 7.7 (1.4,41.7) |
| Asthma/COPD | 7 | 12 | 2.9 (0.6,12.5) |
| Migraine | 2 | 9 | 3.2 (0.3,29.6) |
| NSAID use | 7 | 10 | 4.3 (1.0, 19.1) |
*
Adjusted for age, sex, calendar time and practice in addition to the factors described