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Genotype frequencies among patients showing terodiline cardiotoxicity compared with published control frequencies.
| Polymorphism and genotype | Terodiline cardiotoxicity | Control population |
|---|---|---|
| CYP2D6 | ||
| (n = 8) | (n = 662)* | |
| Wt/wt | 6 (0.75) | 364 (0.55) |
| Mut/wt | 1 (0.125) | 267 (0.40) |
| Mut/Mut | 1 (0.125) | 31 (0.047) |
| CYP2C19 | ||
| (n = 8) | (n = 105) | |
| Wt/wt | 3 (0.375) | 79 (0.75) |
| Mut/wt | 4 (0.50) | 24 (0.23) |
| Mut/mut | 1 (0.125) | 2 (0.02) |
[12, Reference 13.
