Table 1.
Polymorphism and genotype | Terodiline cardiotoxicity | Control population |
---|---|---|
CYP2D6 | ||
(n = 8) | (n = 662)* | |
Wt/wt | 6 (0.75) | 364 (0.55) |
Mut/wt | 1 (0.125) | 267 (0.40) |
Mut/Mut | 1 (0.125) | 31 (0.047) |
CYP2C19 | ||
(n = 8) | (n = 105) | |
Wt/wt | 3 (0.375) | 79 (0.75) |
Mut/wt | 4 (0.50) | 24 (0.23) |
Mut/mut | 1 (0.125) | 2 (0.02) |
[12, Reference 13.