Table 1.

Milk concentrations and M/P ratios for citalopram and demethylcitalopram.

		Citalopram				Demethylcitalopram
Volunteer	tmax (h)	Maximum1 milk concentration (µg l−1)	Average2 milk concentration (µg l−1)	M/PAUC	tmax (h)	Maximum milk concentration (µg l−1)	Average milk concentration (µg l−1)	M/PAUC
1	2.6	210	107	1.4	11.1	67	48	1.4
2	3.8	103	56	0.9	3.8	32	23	1.0
3	3.8	82	53	1.4	2.9	27	23	1.1
4	7.8	186	141	2.0	3.8	48	34	1.5
5	3.5	232	168	1.9	10.8	109	83	1.9
6	3.8	119	83	2.6	1.8	35	29	2.1
7	1.9	147	68	2.3	5.7	34	15	3.3
Mean	3.9	154	97	1.8	5.7	50	36	1.8
(95% CI)	(2.2, 5.6)	(102, 207)	(56, 138)	(1.2,2.3)	(2.2, 9.2)	(23, 77)	(15, 58)	(1.1, 2.5)

¹Maximum value recorded during the dose interval.

²Calculated as AUC(0,24h)/dose interval.