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Mean (± s.e. mean) plasma concentrations of (a) morphine, (b) morphine-6-glucuronide and (c) morphine-3-glucuronide after intravenous administration of 7.5 mg morphine hydrochloride over 2 h with (•) and without (□) coadministration of an intravenous infusion of 150 mg PSC over 2 h starting 1 h earlier (n = 18). Insert: log-linear representation of data.
