Table 1.

Adverse events.

Subject	PSC	PSC + Morphine	Morphine
1	hypoaesthesia *
2		headache *
3		hypoaesthesia *, fatigue *
4	hypoaesthesia *, fatigue *
5		flushing *, GI-discomfort *
6	fatigue *	fatigue *
7			flushing *, somnolence * fatigue †
8	conjunctivitis ‡, fatigue *	flushing *, somnolence *	flushing *, fatigue *
9		metallic taste *
10	flushing †, GI-discomfort †	flushing †, GI-discomfort † paraesthesia*	flushing †, GI-discomfort †
11	drop-out	flushing *, GI-discomfort *	drop-out
12			headache †, fatigue †
13	flushing *, dyspnea *	flushing †, nausea † dyspnea †, hypoaesthesia * paraesthesia *	flushing *, fatigue †
14		orthostatic reaction *
15			fatigue †
16	paraesthesia *	hypoaesthesia *
18			flushing *, dyspnaea * nausea *, tachycardia *
111		nausea *	fatigue *, headache †

intensity:

^*mild

^†moderate

^‡severe.