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a) Cmax (ng ml−1) vs dofetilide dose (µg) on study days 1 (three times daily ▪; twice daily •) and 5 (three times daily □; twice daily ○). b) AUC(0,τ) (ng ml−1 h) vs dofetilide dose on study days 1 (three times daily ▪; twice daily •) and 5 (three times daily □; twice daily ○).
