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Time course of systolic (SBP) and diastolic (DBP) blood pressure, recorded in the supine position, over the first 12 h after administration of placebo (▪ group 1; • group 2) or after the highest administered doses of Z13752A (▴ 600 mg, group 1; ♦ 800 mg, Group 2. Values are expressed as changes from baseline (▵ mmHg). The mean curves for six subjects are shown (eight for placebo).
