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Doxorubicin, etoposide and ifosfamide systemic exposure (AUC at day 1) at cycles 1 and 2 (n = 24 patients; 47 cycles).
| AUC Cycle 1, day1 (mg l−1 h) | AUC Cycle 2, day1 (mg l−1 h) | |||||||
|---|---|---|---|---|---|---|---|---|
| Mean | s.d. | Min | Max | Mean | s.d. | Min | Max | |
| Dox | 1.66 | 0.68 | 0.89 | 6.98 | 1.63 | 0.56 | 0.75 | 2.75 |
| Eto | 94.67 | 19.72 | 44.61 | 122.35 | 88.48 | 23.83 | 57.65 | 142.05 |
| Ifo | 603.63 | 145.21 | 324.41 | 808.56 | 680.85 | 257.73 | 285.97 | 1489.90 |
Dox: Doxorubicin. Eto: Etoposide. Ifo: Ifosfamide.
