Table 2.
Mean (s.d.) GI transit parameters after metformin alone and after pretreatment with metoclopramide and propantheline (n = 11).
| Parameter | Met alone | Met[met] | Met[prop] |
|---|---|---|---|
| GE50% | 6 (5) | 6 (5) | 41 (75) |
| GE90% | 41 (33) | 26 (20) | 187 (138) |
| SITT50% | 216 (50) | 145 (49) | 355 (103) |
| ATC50% | 222 (50) | 151 (52) | 396 (116) |
GE50% and GE90% time (min) to empty 50% and 90%, respectively, of radioactivity from the stomach, SITT50% time (min) to empty 50% of radioactivity from the small intestine, ATC50% time (min) for 50% of radioactivity to arrive at the colon.