Table 2b.

Mean absolute and mean percent change from baseline in ECG parameters following treatment with loratadine, cimetidine, or loratadine plus cimetidine.

Parameter	Cimetidine	Loratadine	Loratadine plus cimetidine
VR (Absolute change (beats min−1) (%)	6.7* (10.2)	9.4* (14.1)	8.9* (12.5)
PR (Absolute change (ms) (%)	2.9 (1.7)	−0.4 (−0.3)	−0.5 (−0.1)
QRS (Absolute change (ms) (%)	−0.8 (−0.8)	−2.0 (−1.9)	−2.2* (−2.2)
QT (Absolute change (ms) (%)	−21.5* (−4.8)	−35.0* (−7.9)	−16.5* (−3.6)
QTc (Absolute change (ms) (%)	−3.2* (−0.8)	−5.4* (−1.3)	−2.3 (−0.5)

^*P ≤ 0.05.