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Pharmacokinetic parameters (mean ± s.d.) following single dose of ABT-627 (Study 1).
| ABT-627 dose | |||
|---|---|---|---|
| Parameter | 1 mg | 20 mg | 40 mg |
| Cmax (ng ml−1) | 1.7 ± 1.0 | 93.5 ± 55.9 | 166.3 ± 131.5 |
| tmax (h) | 6.0 ± 10.8 | 0.6 ± 0.4 | 1.8 ± 0.6 |
| AUC (ng ml−1 h) | 45 ± 19 | 801 ± 257 | 1713 ± 1036 |
| t½ (h) | 26.2 ± 8.3 | 27.6 ± 6.8 | 20.1 ± 3.7 |
