Table 1.

Antidepressants currently marketed in the U.K: Advice re posology in the elderly.

	Posology: Elderly
Tricyclic and related antidepressant drugs
Amitriptyline hydrochloride	Lower starting and maintenance dose
Amoxapine	Lower starting and maintenance dose
Clomipramine hydrochloride	Lower maintenance dose
Dothiepin hydrochloride	Lower starting and maintenance dose
Doxepin	Lower starting and maintenance dose
Imipramine	Lower starting and maintenance dose
Lofepramine	Yes (nonspecific)
Nortriptyline	Yes (nonspecific)
Protriptyline hydrochloride	Lower starting and maintenance dose
Trimipramine	Lower starting and maintenance dose
Maprotiline hydrochloride	Lower starting and maintenance dose
Mianserin hydrochloride	Lower starting dose
Trazodone hydrochloride	Lower starting dose
Viloxazine hydrochloride	Lower starting and maintenance dose
Monoamine oxidase inhibitors (MAOIs)
Phenelzine	No specific advice
Isocarboxazid	Lower maintenance dose
Tranylcypromine	Use with great caution
Moclobemide	No specific advice
SSRIs
Citalopram	Lower maximum dose
Fluoxetine	No specific advice
Fluvoxamine maleate	No specific advice
Paroxetine	Lower maximum dose
Sertraline	No specific advice
Other antidepressant drugs
Flupenthixol	Lower starting and maintenance dose
Mirtazapine	No specific advice
Nefazodone hydrochloride	Lower maintenance dose; Slower dose titration.
Reboxetine	Not currently recommended in elderly
Tryptophan	Yes (nonspecific)
Venlafaxine	No specific advice