Table 4.

Odds ratios crude and adjusted by COC product.

Product	Year of birth controls				5 years banded controls
	Cases	Controls	Unadjusted	Adjusted	Cases	Controls	Unadjusted	Adjusted
LNG 150 µg + Ethinyloestradiol 30 µg	62	224	REFERENCE		64	273	REFERENCE
							1.4 (0.9,2.1)	1.4 (0.9,2.1)
DSG 150 µg + Ethinyloestradiol 30 µg	62	218	1.1 (0.7,1.7)	1.0 (0.6,1.6)	65	223	1.4 (0.9,2.2)	1.5 (0.9,2.3)
GST 75 µg + Ethinyloestradiol 30 µg	60	204	1.1 (0.7,1.7)	1.3 (0.8,2.1)	63	208	1.1 (0.6,2.1)	1.0 (0.5,2.0)
DSG 150 µg + Ethinyloestradiol 20 µg	17	76	0.8 (0.4,1.6)	0.8 (0.4,1.6)	18	76	0.6 (0.4,1.1)	0.6 (0.4,1.0)
Triphasic LNG (50 75 125) + Ethinyloestradiol (30 40 30)µg	25	135	0.7 (0.4,1.1)	0.7 (0.4,1.2)	26	178	1.6 (0.8,3.1)	1.6 (0.8,3 3.2)
NRG 250 µg + Ethinyloestradiol 35 µg	15	51	1.1 (0.6,2.1)	1.1 (0.6,2.3)	15	45	0.7 (0.2,1.8)	0.8 (0.3,2.1)
NRT 500 µg + Ethinyloestradiol 35	4	42	0.3 (0.1,0.9)	0.3 (0.1,1.0)	5	34	2.8 (1.4,5.6)	2.3 (1.1, 4.7)
Cyproterone acetate 2 mg Ethinyloestradiol 35 µg	16	36	1.7 (0.9,3.3)	1.4 (0.7,2.9)	16	26	0.8 (0.5,1.3)	0.9 (0.5,1.4)
BMI < 20	26	155	0.8 (0.5,1.3)	0.7 (0.5,1.2)	28	158	1.3 (0.8,1.8)	1.2 (0.8,1.8)
BMI 20–25	110	537	REFERENCE		115	540	REFERENCE
BMI 25–30	54	164	1.6 (1.1,2.4)	1.6 (1.1,2.3)	56	209	1.3 (0.8,1.8)	1.2 (0.8,1.8)
BMI 30–35	25	62	2.0 (1.2,3.3)	1.9 (1.1,3.2)	25	53	2.1 (1.2,3.6)	2.0 (1.1,3.4)
BMI 35 +	19	20	4.8 (2.5,9.3)	3.8 (1.8,8.0)	19	34	2.6 (1.4,4.7)	2.0 (1.0,3.9)
Unknown BMI	51	160	1.7 (1.1,2.5)	1.1 (0.7,1.8)	53	178	1.5 (1.0,2.2)	1.0 (0.6,1.7)
No asthma	231	987	REFERENCE		240	1084	REFERENCE
Asthma	54	111	2.2 (1.5,3.2)	1.9 (1.3,2.9)	56	88	3.1 (2.1,4.5)	2.5 (1.6,3.8)
Non smoker	141	712	REFERENCE		150	741	REFERENCE
Smoker	102	302	1.8 (1.4,2.5)	2.0 (1.4,2.7)	102	347	1.5 (1.1,2.0)	1.5 (1.1,2.1)
Smoking unknown	42	84	3.1 (1.9,5.0)	2.9 (1.7,5.1)	44	84	3.1 (2.0,4.9)	3.0 (1.7,5.9)
Diastolic BP < 90 mmHg	243	1012	REFERENCE		249	1069	REFERENCE
Diastolic BP 90 mmHg and over	17	34	2.0 (1.0,3.7)	1.1 (0.5,2.3)	18	48	1.6 (0.9,2.9)	1.3 (0.7,2.6)
BP unknown	25	52	2.3 (1.3,3.9)	1.5 (0.8,2.9)	29	55	2.5 (1.5,4.2)	1.7 (0.9,3.2)
0 non-OC scripts	60	397	REFERENCE		62	434	REFERENCE
1–2 non-OC scripts	86	370	1.5 (1.0,2.3)	1.6 (1.0,2.5)	92	388	1.6 (1.2,2.3)	1.6 (1.1,2.3)
3 and more non-OC scripts	139	331	2.5 (1.8,3.5)	2.2 (1.7,3.7)	142	350	2.9 (2.1,4.0)	2.3 (1.6,3.3)
Exposure < 6months	120	373	1.4 (1.1,1.9)	1.3 (1.0,1.8)	127	432	1.3 (1.0,1.7)	1.1 (0.8,1.5)
Exposure 6 months or more	165	725	REFERENCE		169	740	REFERENCE

Note: statistically significant ORs(at the 5% level) are shown in bold.