Table 4.

Summary of 95% confidence intervals (CI) and P values for the pharmacokinetic parameters of ziprasidone on day 8.

	AUC(0,12 h) Ratio of geometric means (%)		Cmax Ratio of geometric means (%)		tmax
Day 8	95% CI	P value	95% CI	P value	95% CI	P value
Normal vs mildly impaired renal function	50,94	0.0221	53,103	0.0724	−2,1	0.4705
Normal vs moderately impaired renal function	83,158	0.3857	91,179	0.1520	−2,1	0.7721
Normal vs severely impaired renal function	76,144	0.7784	70,138	0.9291	−2,1	0.3143
Mildly impaired vs moderately impaired renal function	122,230	0.0025	124,243	0.0022	−1,2	0.6642
Mildly impaired vs severely impaired renal function	111,210	0.0113	96,188	0.0865	−2,1	0.7721
Moderately impaired vs severely impaired renal function	66,125	0.5556	55,108	0.1292	−2,1	0.4705