Table 2.
Mean± s.d. values of ziprasidone and paroxetine pharmacokinetic parameters.
| Treatment group | ||
|---|---|---|
| Pharmacokinetic parameter | Ziprasidone (n = 8) | Paroxetine (n = 7)a |
| AUC(0,10 h) (ng ml−1 h) | 311 ± 157 | 32.9 ± 17.1 |
| Cmax (ng ml−1) | 55 ± 35 | 6 ± 4 |
| tmax (h) | 4 ± 1 | 6 ± 2 |
Excludes one subject who received paroxetine but in whom the drug was not detectable in plasma during the 10 h postdose sampling period.