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. 1997 Mar 18;94(6):2711–2714. doi: 10.1073/pnas.94.6.2711

Figure 3.

Figure 3

Figure 3

Effects of the Gβ115–135 peptide on AC2 and AC1 activities. (A) Ribbon diagram of the Gβ1 backbone with residues 115–135 in yellow. Other residues in contact with the AC2 peptide are shown in pink. (B) Effect of the Gβ115–135 peptide (GGL) and the Y124V-Gβ115–135 mutant peptide (m-GGL) on basal, αs* (2 nM), and αs* (2 nM) plus Gβγ (50 nM) stimulated AC2 activities. (C) Effect of GGL and m-GGL peptides on basal, CaM (100 nM), or CaM (100 nM) plus Gβγ (30 nM) regulated AC1 activities.