Figure 1.

Blockage of K⁺ currents by EEDQ. Depolarizing pulses (3 sec) to −80 mV and beyond elicited a K⁺ current that was appreciably reduced by 5 × 10⁻⁴ M EEDQ. Oocyte previously injected with newborn rat spinal cord mRNA to induce K⁺ channels. Membrane potential held at −100 mV between pulses.